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SVP, Cancer Biology

Circle Pharma

South San Francisco, CA, US
  • Job Type: Full-Time
  • Function: Life Sciences R&D/Engineering
  • Industry: Biotechnology
  • Post Date: 07/15/2024
  • Website:
  • Company Address: 681 Gateway Blvd, 3rd Floor, South San Francisco, California, 94080

About Circle Pharma

Circle Pharma is an early-stage biotechnology company applying proprietary computational design algorithms and innovative chemistry to develop cell-permeable macrocycle peptide therapeutics against important clinical targets. It does this through an iterative, rational design process that deploys large virtual libraries of conformationally diversemacrocycle scaffolds selected for inherent permeability.

Job Description

Circle Pharma is a dynamic biotech company advancing the discovery and development of cell-permeable oral macrocycles. Our platform combines structure-based drug design and advanced synthetic chemistry to create first-in-class macrocycle therapeutics for severe unmet clinical needs. We are focusing our development efforts on cyclins, which are master regulators of the machinery that controls progression of cells through the cell cycle and are key drivers in many cancers.
We seek passionate individuals poised to drive our growth and make a difference. Learn more about Circle Pharma at
We are seeking a visionary leader to join our team as the Senior Vice President and Head of Cancer Biology. Reporting directly to our CEO, the Head of Cancer Biology will lead and oversee all aspects of biology and translational sciences within Circle Pharma. This individual will collaborate closely within the organization to drive innovation, ensure alignment with our organizational goals, and foster a cohesive and integrated approach to drug development.

What You'll Do:

    • Oversee the full range of biological sciences underpinning our cancer drug discovery programs from new target identification to translational sciences support for clinical programs, including establishing scientific strategies, timelines, and resourcing priorities.
    • Collaborate closely with the heads of Discovery Technology Sciences and Early Clinical Development to ensure integration of the company’s biological sciences capabilities at project initiation through to clinical proof-of-concept.
    • Drive the development and implementation of translational strategies to optimize the clinical development pathway.
    • Lead a multidisciplinary team, fostering a culture of excellence, synergy, and innovation.
    • Engage with pharma partners to drive partnered research programs.
    • Participate as a member of the company’s Executive Leadership Team to drive company strategy, culture, and leadership.
    • Provide strategic leadership and guidance to direct reports, including Vice Presidents, to ensure alignment with Circle’s objectives while nurturing a culture of collaboration, scientific excellence, and a drive for results

About You:

    • MD/PhD, or PhD in biology, molecular biology, biochemistry, or related field with demonstrated achievements evidenced by patents, publications, and products.
    • Minimum of 15 years of experience in oncology drug discovery in positions of increasing responsibility, with a track record of advancing programs from early discovery to clinical trials.
    • Deep knowledge of cancer biology and oncogenic pathways.
    • Strong experience in translational science and biomarkers, spanning research through clinical development.
    • Proven leadership experience in a biotech or pharma setting, with demonstrated ability to build, lead and inspire teams to achieve ambitious goals.
    • Comfortable in a small, fast-moving, and growing company environment, driving decisions with a close focus on achieving results.
    • Demonstrated success working in a cross-functional, matrixed organization, with a track record of effective collaboration and partnership across disciplines and functions.
    • Excellent written and verbal communication skills, with the ability to communicate complex scientific concepts effectively to diverse audiences.
    • Active listener who enjoys operating in an exceptionally dynamic, high-achieving, and cooperative environment where every voice matters.
    • Demonstrated willingness to lead, champion, and operate with Circle’s Core Values.
$310,000 - $365,000 a year
This position is an in-person role based at our facility in South San Francisco.  The anticipated salary range is $310,000 to $365,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, education, etc.
Circle Pharma recognizes that the success of our endeavors depends on the success of every team member. Your well-being is our top priority, and we are proud to offer a comprehensive total rewards package. Our benefits include but are not limited to medical, dental, and vision care. We also provide a 401(k) plan with a generous company contribution, and all of our offers contain a stock option component. We provide company-paid life insurance, short-term and long-term disability. Additionally, we provide many company-paid holidays, including a winter break at the close of the calendar year. 
Circle Pharma is an equal opportunity employer and committed to a diverse workplace. All applicants will be considered equally without regard to race, color, ethnicity, veteran status, religion, national origin, marital status, political affiliation, age, sex, sexual orientation, gender identity, disability status, membership in an organization or any other non-merit factors.

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