Job Description

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

This is a unique opportunity for a Clinical Operations Financial and Contracts Professional who has innate leadership and organizational skills, technical expertise in clinical oncology drug development in an industry setting, and experience in organizing and overseeing key clinical trial systems. As a Sr. Director you will be responsible for operational design, team structure of and accountable for the oversight and general execution of financial, contractual, and business systems, vendor relationships to contribute to the highest quality with on time delivery of RevMeds clinical studies.

Required Skills, Experience and Education:

• Establish a governance, structured approach to Clinical Finance and Vendor contracting/budgeting.

• Develop and establish cross functional relations with development operations teams (clinical, DM, Biometrics, safety, regulatory, quality) as well as Finance and Legal to define and review vendor contract proposals and budgets.

• Provide operational guidance to develop strategic Vendors and clinical research organizations relationships which will provide quality resources and solutions across RevMed clinical programs.

• Establish and develop request for proposal content in support of clinical studies and lead the vendor selection process on a study and portfolio basis.

• Establish a governed, structured approach to Review work orders, change orders and consulting agreements according to the scope of services requested.

• Accountable for templates with the clinical vendors which align to the best clinical practices and responsibilities.

• Successful planning and deployment of financial processes within clinical operations for purchase orders and invoice processing.

• Enable collaborative and communicate effectively with all functional area representatives, in the project team environment as needed to ensure alignment across functions to support clinical programs.

• Establish oversight and, structured approach for Legal and Finance to review, amend and negotiate Master Service Agreements with vendors.

• Provide strategic contributions to QA and IT for completion of vendor qualification as required under SOPs

• Accountable for overall financial and vendor management of multiple clinical trials across all clinical study vendors.

• Contributes expertise to coordinate and ensure vendor agreements cover all operational activities for a successful clinical trial

• Lead internal and external logistics and/all activities/services required to streamline execution of vendor agreements and purchase orders.

• Initiates, cultivates and maintains strong relationships with vendors and the study teams they support.

• Create and manage systems and processes required for seamless communication with the Clinical Stakeholders.

• Strategic contributor to the development, management, and execution of evidence gathering and Clinical Development Plan (CDP) for assigned clinical programs which includes timelines, budget, and resource requirements.

• Ability to identify critical path activities and articulate and mitigate risks to clinical trial conduct.

• Successful planning and deployment of Clinical Operations staff for project and non-project related tasks. Establish clear roles and responsibilities for team members and include opportunities to stretch skills and enable growth.

• Line management responsibilities include hiring, performance management, career development, and mentorship.

• Provide information on studies and programs to enable oversight on vendor executed budgets and communicate with business owner budget risks.

• Participate in and/or lead vendor governance activities for key CRO/vendor partners.

• Support clinical program teams with long range planning, scenario analysis, and annual budget planning activities.

• Recommend and implement innovative processes to improve and impact clinical trial management and deliverables including contingency plans.

• Minimum of a BS, plus 10-15 years of experience in a finance and contract administration environment in a pharmaceutical, CRO/ biotech company or worked in a clinical operations setting with a CRO/Sponsor company Advanced degree desirable.

• Experience in evaluating, negotiating, and managing multiple successful relationships with partners, ability to set up milestones to track progress and collaborating with partners.

• Expertise in large, multi-site, Phase 3 clinical trials.

• Experience working in growing companies or departments that have created successful processes.

• Direct experience with vetting and negotiating with vendors is necessary.

• Ability to understand the clinical development process and demonstrate the capability of managing multiple external vendors for multiple clinical trials simultaneously.

• Comfortable in a fast-paced company environment and able to adjust workload based upon changing priorities.

• Demonstrated leadership qualities, including the ability to say "no." and teamwork.

• Prior Management experience knowledge of applicable regulatory and ICH guidance regarding clinical research and GCP.

• Decision-making skills

• Demonstrated ability to multi-task, prioritize work, and independently solve problems in a rapidly changing environment.

• Excellent interpersonal, verbal, and written communication skills, with ability to interact with colleagues and partners at all levels of experience.

• An analytical thinker who can efficiently utilize company resources and expertise to extract optimal vendor performance.

• A strong person with the "backbone" and credibility, both internally and externally, to successfully negotiate contracts beneficial to the Company.

• An excellent communicator, both written and verbal, with the ability to train and present data, complex protocol designs etc. and influence internal and external colleagues as required.

• Strong strategic/conceptual skills that can bridge the gap between different interdisciplinary departments, (medical affairs, commercial and other disciplines) to build a formidable team.

• Experience with hiring, training, developing, mentoring, and motivating team members to the highest level of performance

• Excellent organizational skills and attention to detail.

• An innovative, driven, and effective person with a "can do" attitude.

• A goal-oriented person who can plan for the long-term and execute stated objectives.

• Strong working knowledge of FDA Regulations, ICH Guidelines, and GCP related to late stage or post marketed products.

• Demonstrate proficiency in Microsoft Office Suite (Outlook, MS Word, Excel, PowerPoint); MS Project and/or Smartsheet a plus.

• Travel may be required (~25%).

Preferred Skills:

• Familiarity working with financial and legal systems/portals.

• Oncology experience, early and/or late stage, strongly preferred.

• Knowledge and/or familiarity with Ex-US region(s) clinical trial operations.

The base salary range for this full-time position is $236,000 to $295,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.