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Senior Research Associate, Biology

Nura Bio

South San Francisco, CA, US
  • Job Type: Full-Time
  • Function: Research Sci/Assoc/Mgr
  • Industry: Biotechnology
  • Post Date: 10/13/2024
  • Email: joinus@nurabio.com
  • Website: nurabio.com
  • Company Address: 161 Oyster Point Blvd, South San Francisco, California, 94080
  • Salary Range: $50,000 - $150,000

About Nura Bio

At Nura Bio (previously known as Proneurotech Inc.), we envision a world where the diagnosis of a neurological disorder comes with the hope of a cure. Expanding on recent breakthroughs in crucial neurodegenerative pathways, we are positioned to deliver transformative neuroprotective therapies to prevent and protect against neuronal loss and related neuroimmune dysregulation.

Job Description

Nura Bio, Inc. (Nura Bio) is a clinical-stage biopharmaceutical company developing neuroprotective therapies for the treatment of a broad range of neurological diseases. Nura Bio’s research and early development small molecule pipeline is focused on developing therapies that halt axon degeneration and/or modulate microglial responses to degeneration and injury, with the goal of conferring neuroprotection, across diseases of the central, peripheral, and ocular nervous system.
 
We are looking for a highly motivated Senior Research Associate in the Biology team to conduct exciting research at Nura Bio in the areas of in vitro and in vivo neurobiology. As a member of the Nura Bio team, you will be part of a culture of scientific excellence, rigorous innovation, and collaboration. 
 
Nura Bio offers a comprehensive generous medical and dental insurance, vision, life and disability insurance, health savings account, flexible savings, and dependent care, 401(k) plan, and highly attractive stock options.
 
Nura Bio is proud to be an equal opportunity employer and will consider all qualified applicants for employment.
 
To learn more about our mission and our science, visit us at www.nurabio.com. If you have the experience we are seeking and would like the opportunity to contribute to our mission, we would like to hear from you!
 
Please send your CV with a cover letter delineating why you are interested to joinus@nurabio.com
 
 
What You Will Do:
  • Work under the guidance and mentorship of scientists to evaluate novel neuroprotective therapeutics in model in vitro cell systems
  • Participate in the design and development of novel cell-based assays in medium-high throughput formats to drive new target validation, compound optimization and MoA studies
  • Establish relevant mammalian cell, primary or iPSC cultures, including differentiation of iPSCs to microglia, neurons, or other cells and optimize genetic manipulation of iPSC and primary cell systems
  • Keep detailed and organized records of experimental protocols and results
  • Analyze and interpret results, and communicate and present key findings at team meetings
  • Rely upon your keen analytical and problem-solving skills to troubleshoot technical issues and implement solutions
  • Keep current with scientific literature relating to neurodegeneration
  • Collaborate and communicate across a diverse scientific team to successfully progress scientific goals
  • Rely on your strong interpersonal and communication skills to build transparent and collaborative relationships
  • Work on multiple projects simultaneously within a functional area
What You Will Bring:
  • A Bachelors degree in Biochemistry, Molecular/Cell Biology, or related discipline with 7+ years or Master’s degree with 3+ years of hands-on research experience
  • Experience with lentiviral transduction, stable cell line development, CRISPR-based gene editing
  • Basic techniques in cell culture; experience with culture and differentiation protocols for iPSCs is desirable
  • Experience with cell-based assay development
  • Experience with performing medium- to high- throughput assays and analyzing large datasets
  • Keen analytical and problem-solving skills, and the ability to resolve complex problems requiring innovative, custom solutions
  • The ability to manage multiple tasks efficiently, communicate clearly, and build open and collaborative relationships is essential
  • Ability to independently analyze and interpret data (e.g., GraphPad Prism, Origin, R, etc.)
  • Background knowledge in neuroinflammation or neurodegeneration is desirable

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