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Senior Computational Biologist, Genomics

Revolution Medicines

Redwood City, CA, US
  • Job Type: Full-Time
  • Function: Life Sciences R&D/Engineering
  • Industry: Biotechnology
  • Post Date: 11/22/2022
  • Website:
  • Company Address: 700 Saginaw Drive, Redwood City, CA, 94063

About Revolution Medicines

REVOLUTION Medicines discovers and develops new drugs that harness the therapeutic potential of frontier oncology targets on behalf of cancer patients. Our innovative product engine draws inspiration from nature and evolution, which offer insights into cancer targets, disease mechanisms and therapeutic approaches.

Job Description

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit high-value frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

As a Computational Biologist, you will:

  • Work closely with experimental scientists to prioritize and develop computational analysis plans.

  • Employ your expertise to distill meaning from complex datasets.

  • Explore and integrate multi-omic datasets that include DNA mutation, gene expression, copy-number, and modalities including single-cell assays.

  • Contribute to the development of analysis pipelines and computational tools.

  • Work closely with scientists, contract research organizations, and other collaborators to answer key questions related to our research.

  • Communicate the results of your work to internal and external stakeholders.

Required Experience, Skills, and Education:

  • Ph.D. in bioinformatics, genetics, or related field.

  • 3+ years of experience with a focus on the analysis of NGS data is strongly desired.

  • Expertise in statistical methods as applied to high-throughput biological experiments.

  • Strong knowledge of molecular biology and genomics.

  • Proficiency using R, Python, or equivalent.

  • Strong scientific communication skills.

Revolution Medicines currently requires that all personnel and visitors to its offices be fully vaccinated against COVID-19. This role will require that the employee meet with company employees and work from the company’s offices. Given that these essential functions of the role must be performed on-site, this position requires full COVID-19 vaccination, subject to applicable law.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

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