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Senior Director to Executive Director, Head of Clinical Pharmacology

Revolution Medicines

Redwood City, CA, US
  • Job Type: Full-Time
  • Function: Clinical Research
  • Industry: Biotechnology
  • Post Date: 11/22/2022
  • Website:
  • Company Address: 700 Saginaw Drive, Redwood City, CA, 94063

About Revolution Medicines

REVOLUTION Medicines discovers and develops new drugs that harness the therapeutic potential of frontier oncology targets on behalf of cancer patients. Our innovative product engine draws inspiration from nature and evolution, which offer insights into cancer targets, disease mechanisms and therapeutic approaches.

Job Description

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit high-value frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

We are seeking a passionate and energetic individual with strong scientific background and leadership skills to be part of the Nonclinical Development and Clinical Pharmacology (NDCP) Organization. As a key leader in the department, you will

  • Drive Clinical Pharmacology strategic planning and execution to support overall clinical development based on project specific clinical development plan (CDP).

  • Establish functional capacities, deliverables, and budgets to effectively and efficiently influence company strategies and performance.

  • Interact with Research and Development leadership team and provide cohesive direction to support cross-functional teams toward company goals.

  • Build strong working relationships with multi-disciplinary functions and subject matter experts, represent NDCP in Clinical Development Strategy Team (CDST) and internal governance meetings, and provide clinical pharmacology insights to impact critical project decisions.

  • Represent the Clinical Pharmacology function in project development teams. Design and execute dedicated clinical pharmacology studies to deliver key data and interpret potential implications to the project team.

  • Maintain up to date knowledge of current regulatory practice, provide regulatory strategy expertise for filings, and author clinical pharmacology sections of regulatory documents and responses to regulatory questions.

  • Engage with consultants and/or CROs on clinical pharmacology activities to complement in-house knowledge/expertise and capacities.

  • Manage and mentor junior stuff within the Clinical Pharmacology function and provide technical leadership across projects.

Required Experience, Skills, and Education:

  • A Pharm.D. or Ph.D. in Pharmaceutical Sciences, Pharmacokinetics, or a related scientific discipline with over 12 years of relevant industry experience.  

  • Demonstrated experience and track record in running and/or overseeing clinical pharmacology programs and support drug development from IND through regulatory submission.

  • Excellent verbal and written communication skills, and ability to clearly convey complex concepts and findings to both non-specialist and specialist audiences.

  • Strong leadership and interpersonal skills, demonstrated ability to manage multiple priorities, and capability to exercise sound judgment to influence cross functional teams.

  • A critical thinker and passionate team player with high energy who thrives in a dynamic and fast-paced environment.

Revolution Medicines currently requires that all personnel and visitors to its offices be fully vaccinated against COVID-19. This role will require that the employee meet with company employees and work from the company’s offices. Given that these essential functions of the role must be performed on-site, this position requires full COVID-19 vaccination, subject to applicable law.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition and veteran status.

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