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Scientist Discovery Biology, Immunology

Ribon Therapeutics

Cambridge, MA, US
  • Job Type: Full-Time
  • Function: Life Sciences R&D/Engineering
  • Industry: Biotechnology
  • Post Date: 09/19/2022
  • Website: ribontx.com
  • Company Address: 35 Cambridge Park Dr, Suite 300, Cambridge, Massachusetts, 02140

About Ribon Therapeutics

Ribon is a clinical-stage biotechnology company dedicated to the discovery and development of first-in-class small molecule inhibitors to block the fundamental ability of cancer cells to survive under stress.

Job Description

We are seeking a biologist with a background in inflammation/immunology or immune-oncology to join our culture of transparency, intensity, scientific rigor, and fun! The successful candidate will serve as an integral member of a multidisciplinary pre-clinical team that is developing novel small molecule inhibitors for monoARTs. The position is an opportunity to perform in a high visibility role with the possibility to have a major impact in the pre-clinical stages of drug development. Candidates with a track record in early-stage drug discovery research in either a pharma setting or in academia will be considered.

Responsibilities

  • The candidate will work as part of a pre-clinical team to support ongoing drug discovery, pre-clinical, and clinical programs.
  • The candidate will independently evaluate the literature and design/execute/interpret cell-based assays, using mouse and human primary cells and cell lines, to drive mechanism of action studies.
  • The candidate will be provided opportunities to manage outsourced FTEs and projects at appropriate CROs.
  • The candidate will communicate scientific results among the scientific teams.

Requirements

  • MS/Ph.D. in immunology, inflammation, cancer biology, cell biology, biochemistry, or a related field.  
  • A minimum of 5 years of relevant laboratory experience.
  • 0-5 years of drug discovery experience in biotechnology or pharmaceutical industry.
  • Extensive mammalian tissue culture experience is required. Experience isolating and culturing primary human and mouse immune cells is a plus.
  • Experience with flow cytometry, transcriptional analysis (qPCR), protein and cytokine measurements (ELISA/Luminex/MSD) are required.
  • Hands-on experience in immunology/inflammation is an advantage.
  • Expertise in cell biology, biochemistry, molecular biology, and genome editing are desired.
  • Proven experience in the critical and independent evaluation of the scientific literature is a must.
  • Proficient in experimental design, assay development, execution of experiments, data analysis, interpretation, and presentation.
  • Excellent problem-solving skills and an ability to take on new challenges.
  • The successful candidate is able to work independently yet thrives in a team environment.
  • Ability to work well under pressure and drive projects that affect critical timelines.
  • Excellent organizational skills and attention to detail.

About Ribon Therapeutics

Ribon Therapeutics is a biotechnology company pioneering the discovery of new cancer medicines that target monoPARP proteins, critical regulators of cancer survival mechanisms. Ribon offers a fast-paced, team-oriented work environment and a comprehensive benefits package, including health, dental, 401(k), paid vacation, and much more.  Ribon is located in Cambridge, Massachusetts.

Ribon Therapeutics is an equal opportunity employer

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